Clinical Study of Camrelizumab Combined With TCb Versus TCb in Neoadjuvant Treatment of Triple-negative Breast Cancer
Recruiting
Phase 2
Interventional Study
Breast Cancer
Triple Negative Breast Cancer
Camrelizumab
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 – 70
- Sex
- Female
- Trial phase
- Phase 2
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 369 (estimated)
- Sponsor
- Zhenzhen Liu · Government
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About This Trial
Triple-negative breast cancer (TNBC) is a special subtype of breast cancer that lacks the expression of ER, PR, and Her-2 proteins, accounting for 15%-20% of all breast cancers.TNBC patients do not benefit from endocrine therapy or HER-2-targeted therapy, but are sensitive to cytotoxic drug therapy.Although the survival of TNBC patients has improved significantly compared with the past, it is stil…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Age: 18-70 years old
2. cT2 - cT4d, or cT1c with axillary lymph node metastasis confirmed clinically and pathologically;
3. Pathologically proven triple negative breast cancer:
Triple-negative breast cancer is defined as:
* Negative for ER and PR (IHC nuclear staining …
Contacts