Chinese Longitudinal and Systematic Study of Bioplar Disorder
Recruiting
N/A
Interventional Study
Major Depressive Disorder
Bipolar Disorder, Mixed
Affective; Disorder, Organic
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 16 – 65
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 10,000 (estimated)
- Sponsor
- First Affiliated Hospital of Zhejiang University · Other
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About This Trial
Affective disorders (mainly including major depressive disorder and bipolar disorder) are common, chronic and highly disabling mental disorders, which lack of objective biological markers. It is believed that genetic and environmental factors are involved in the development of affective disorders. Gut microbes can affect the function of brain neural circuits by mediating metabolic, immune, endocri…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Both biological parents are Han nationality;
2. Aged 16-65;
3. The subjects met the clinical diagnostic criteria of DSM-5 for depressive episodes of MDD/BD;
4. Did not take any immunomodulatory preparations within 1 month before enrollment;
5. No clear history of respiratory …
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