An Exploratory Study to Evaluate Immune Determinants of the Response to Adoptive Cell Therapy (ACT) in Solid and Hematologic Tumors

Recruiting N/A Interventional Study
Solid Tumor, Adult Solid Tumor, Childhood Hematologic Cancer
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
2 and older
Sex
Any
Study type
Interventional
Purpose
Other
Participants needed
160 (estimated)
Sponsor
Gustave Roussy, Cancer Campus, Grand Paris · Other
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About This Trial
This is a study to explore the phenotypic and transcriptional changes of different cellular components in the tumor following the injection of somatic cell therapy drugs. The second objective is to explore phenotypic and transcriptional changes of different cellular components in blood and bone marrow following injection of somatic cell therapy drugs.Then correlate the phenotypic and transcriptio…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Patient affiliated to a social security regimen * Tumor lesion accessible to core biopsies * Patient who is fully informed, able to comply with the protocol and who signed the informed consent * Pediatric patients \> than 2 years old can be included * No restriction about the …
Contacts

Camille BIGENWALD, MD

+33 (0)1 42 11 42 29

camille.bigenwald@gustaveroussy.fr

CONTACT

Cristina CASTILLA LLORENTE, MD

+33 (0)1 42 11 42 39

cristina.castilla-llorente@gustaveroussy.fr

CONTACT