Weight Tracking and GRAIL Galleri Testing for Unintentional Weight Loss
Unintentional Weight Loss and Cancer: A Prospective Trial of Patient-centered Weight Tracking Combined With GRAIL Galleri Testing to Improve Early Detection
Recruiting
N/AInterventional Study
Unintended Weight Loss
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
40 – 80
Sex
Any
Study type
Interventional
Purpose
Screening
Participants needed
1,000 (estimated)
Sponsor
Case Comprehensive Cancer Center · Other
Who this trial is looking for
This trial is looking for people aged 40 to 80 who have experienced unintentional weight loss. Participants will track their weight weekly and take part in a cancer detection test.
Are You a Good Fit for This Trial?
You may be able to join if
I am between 40 and 80 years old.
I have access to a device compatible with the Fitbit Aria Air smart scale.
I can commit to all study procedures for the duration of the trial.
I am mentally competent and can sign a consent form.
I speak English.
You may not be able to join if
I have an active cancer diagnosis.
I am currently receiving cancer treatment.
I have completed cancer treatments within the last 3 years.
I am actively trying to lose weight with medications or surgery.
I am pregnant.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Unintentional weight loss (UWL) is commonly associated with a wide variety of diseases and there is still no valid diagnostic pathway for evaluating UWL. When detecting UWL coupled with GRAIL Galleri testing, (an investigational pan-cancer early detection test), it is thought that there is a greater positive predictive value in detecting malignancies. This study aims to test the potential synergis…
Unintentional weight loss (UWL) is commonly associated with a wide variety of diseases and there is still no valid diagnostic pathway for evaluating UWL. When detecting UWL coupled with GRAIL Galleri testing, (an investigational pan-cancer early detection test), it is thought that there is a greater positive predictive value in detecting malignancies. This study aims to test the potential synergistic effects of UWL detection and GRAIL usage to detect malignancy at an even earlier rate. UWL will be measured using weekly weight tracking.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age range: from 40 to 80 years
* Access to a device (cellphone, computer, tablet) that is compatible with the Fitbit Aria Air smart scale utilized in this study
* Willing to comply with all study procedures and be available for the duration of the study
* Subjects must be ment…
Inclusion Criteria:
* Age range: from 40 to 80 years
* Access to a device (cellphone, computer, tablet) that is compatible with the Fitbit Aria Air smart scale utilized in this study
* Willing to comply with all study procedures and be available for the duration of the study
* Subjects must be mentally competent and must have the ability to understand and the willingness to sign a written informed consent document
* Subjects must speak English to maximize chance of understanding the trial rational and study procedures
Exclusion Criteria:
* Active cancer diagnosis - current diagnosis, currently undergoing cancer treatment, or concluded cancer treatments within 3 years
* Actively trying to lose weight with medications or bariatric surgery
* Pregnant
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