Brain Activity Study for Parkinson's Disease

Sensory Filtering in the Human Basal Ganglia as a Mechanism of Parkinson's Disease

Recruiting Observational Study
Parkinson Disease
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part. No Study Drug Researchers observe your health over time — no experimental treatment is given.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 89
Sex
Any
Study type
Observational
Participants needed
30 (estimated)
Sponsor
University of Alabama at Birmingham · Other
Who this trial is looking for

This trial is looking for adults with advanced Parkinson's disease and healthy individuals without neurological conditions. Participants will help researchers understand brain activity related to movement disorders and may undergo deep brain stimulation surgery.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am over 18 years old.
  • I have been diagnosed with advanced Parkinson's disease.
  • I have a normal brain MRI before the surgery.
  • I can attend follow-up visits during the study.
  • I have chosen to have deep brain stimulation surgery.
  • I am assigned to have surgery in the subthalamic nucleus.

You may not be able to join if

  • I am under 18 years old.
  • I have health issues that could complicate surgery.
  • I have been diagnosed with other types of Parkinsonism.
  • I have a psychogenic movement disorder.
  • I have had prior brain surgery for my condition.
  • I have clinical dementia.
  • I cannot stop my Parkinson's medications for at least 12 hours before visits.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial

The investigators are investigating the brain activity associated with sensory information in movement disorders in order to improve treatment of these symptoms beyond what is currently available.

Trial Locations
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Eligibility Criteria
Inclusion criteria (PD participants): 1. Age \>18 years 2. Clinically definite, advanced idiopathic PD based on consensus criteria. 3. Normal, or essentially normal, preoperative brain MRI. 4. Patient is available for follow-up visits over the length of the study 5. Patient has elected to undergo D…
Contacts

Zachary Irwin, PhD

(205) 934-6704

zirwin@uabmc.edu

CONTACT