No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
15 (estimated)
Sponsor
Medical University of South Carolina · Other
Who this trial is looking for
This trial is looking for people with neuropathic pain from a spinal cord injury to participate in training that may help reduce their pain. Taking part involves about 50 visits over roughly 6.5 months.
Are You a Good Fit for This Trial?
You may be able to join if
I am neurologically stable and more than 1 year post spinal cord injury.
I have medical clearance to participate.
I can stand for at least 3 minutes with or without help.
I expect my current medication will stay the same for at least 3 months.
My neuropathic pain includes the lower leg.
You may not be able to join if
I have a motoneuron injury.
I have a known cardiac condition.
I have a medically unstable condition.
I have cognitive impairment.
I have uncontrolled peripheral neuropathy.
I frequently use electrical spinal stimulation for pain treatment.
I use electrical stimulation on my leg daily.
I have a complete lack of sensation around my foot.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
The purpose of the second part of the study is to examine the effect of reflex training in the leg to decrease neuropathic pain. For this, the researchers are recruiting 15 individuals with neuropathic pain due to spinal cord injury to participate in the reflex training procedure. The study involves approximately 50 visits with a total study duration of about 6.5 months (3 months for baseline and …
The purpose of the second part of the study is to examine the effect of reflex training in the leg to decrease neuropathic pain. For this, the researchers are recruiting 15 individuals with neuropathic pain due to spinal cord injury to participate in the reflex training procedure. The study involves approximately 50 visits with a total study duration of about 6.5 months (3 months for baseline and training phases followed by 1 month and 3 month follow-up visits).
Trial Locations
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Status
Eligibility Criteria
Inclusion Criteria:
1. neurologically stable (\>1 year post SCI)
2. medical clearance to participate
3. ability to stand with or without an assistive device for at least 3 minutes at a time
4. expectation that current medication will be maintained without change for at least 3 months (stable use of…
Inclusion Criteria:
1. neurologically stable (\>1 year post SCI)
2. medical clearance to participate
3. ability to stand with or without an assistive device for at least 3 minutes at a time
4. expectation that current medication will be maintained without change for at least 3 months (stable use of anti-spasticity medication is accepted)
5. For participants with neuropathic pain, the area of neuropathic pain must include lower leg.
Exclusion Criteria:
1. motoneuron injury
2. known cardiac condition
3. medically unstable condition (incl. pregnancy)
4. cognitive impairment
5. uncontrolled peripheral neuropathy
6. frequent use of electrical spinal stimulation (either transcutaneous or epidural) for pain treatment
7. daily use of electrical stimulation to the leg
8. complete lack of cutaneous sensation around foot.
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