Personalized Mechanical Ventilation Guided by UltraSound in Patients With Acute Respiratory Distress Syndrome
Recruiting
N/A
Interventional Study
ARDS, Human
Lung Ultrasound
Mechanical Ventilation
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 – 100
- Sex
- Any
- Study type
- Interventional
- Purpose
- Supportive Care
- Participants needed
- 538 (estimated)
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Other
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About This Trial
Rationale Acute respiratory distress syndrome (ARDS) is a frequent cause of hypoxemic respiratory failure with a mortality rate of approximately 30%. The identification of ARDS phenotypes, based on focal or non-focal lung morphology, can be helpful to better target mechanical ventilation strategies of individual patients. Lung ultrasound (LUS) is a non-invasive tool that can accurately distinguish…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Admitted to a participating ICU,
* invasively ventilated and
* fulfil the Berlin criteria for moderate or severe ARDS.
Exclusion Criteria:
* Age under 18,
* participation in other interventional studies with conflicting endpoints,
* conditions in which LUS is not feasible or…
Contacts