[68Ga]Ga-PentixaFor PET/CT in Acute Myocardial Inflammation
Recruiting
Phase 2
Interventional Study
Acute Cellular Graft Rejection
Cardiac Sarcoidosis
Myocarditis Due to Drug
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Phase 2
- Study type
- Interventional
- Purpose
- Diagnostic
- Participants needed
- 69 (estimated)
- Sponsor
- John O. Prior · Other
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About This Trial
Acute myocardial inflammation is an heterogenic syndrome involving different clinical pathologies with different outcome. For the purpose of this study protocol, we focuse on three entities of this syndrome, namely the acute cellular cardiac allograft rejection (ACR), cardiac sarcoidosis (CS) and the immune checkpoint inhibitor induced myocarditis (ICIM), for which non-invasive diagnosis remains c…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* signed written informed consent
* male or female
* age ≥ 18 years
* patients with suspicion CS (group II) or ICIM (group III) or in their regular follow-up in their first year after HT (group I)
* SOC clinical follow-up at the cardiology department in CHUV.
Exclusion Criteria…