Neoadjuvant Furmonertinib Plus Bevacizumab or Furmonertinib Monotherapy for Resectable and Potentially Resectable Stage III-IVA EGFR Mutation-Positive Lung Adenocarcinoma

Recruiting Phase 2 Interventional Study
Lung Adenocarcinoma Stage III Lung Adenocarcinoma Stage IV EGFR Gene Mutation
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
96 (estimated)
Sponsor
Shanghai Pulmonary Hospital, Shanghai, China · Other
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About This Trial

To explore the efficacy and safety of neoadjuvant furmonertinib combined with bevacizumab in the treatment of resectable and potentially resectable stage III-IVA EGFR mutation-positive lung adenocarcinoma.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Lung adenocarcinoma patient with EGFR sensitive mutation as confirmed by needle biopsy; * At stage III-IVA (TNM Staging, Version 8) as identified by chest CT, PET-CT or/and EBUS; * No systemic metastasis (confirmed by head MRI, whole body bone scan, PET-CT, liver and adrenal C…
Contacts

Peng Zhang, MD,PhD

+8613512185932

zhangpeng1121@outlook.com

CONTACT