Digital Therapy for Depression After Stroke

A Digital Intervention for Post-Stroke Depression and Executive Dysfunction

Recruiting Phase 2 Interventional Study
Executive Dysfunction Depression Stroke
Prior Safety Data This treatment has already been tested in at least one earlier human trial.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
50 – 79
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
70 (estimated)
Sponsor
Weill Medical College of Cornell University · Other
Who this trial is looking for

This trial is looking for people who have had a stroke at least 6 months ago and experience depression and cognitive difficulties. Participants will use an iPad-based program and learn new cognitive strategies to help improve their symptoms.

Are You a Good Fit for This Trial?
Must be taking Antidepressants

You may be able to join if

  • I have had a first-time stroke at least 6 months ago.
  • I have problems with executive function as shown in a test.
  • I have been diagnosed with a Major Depressive Episode.
  • I have moderate depressive symptoms.
  • I can use an iPad and a pen.
  • I have been on a stable dose of antidepressant medication for at least 8 weeks.
  • I can follow all study requirements and commit to the study duration.

You may not be able to join if

  • I have severe speech problems that affect my understanding.
  • I have speech issues that make it hard to talk.
  • I have severe vision issues or neglect of one side of my body.
  • I am already in another cognitive rehabilitation program.
  • I do not speak English well.
  • I have a significant neurologic condition besides my stroke.
  • I have dementia that affects my daily living.
  • I have a history of psychosis or mania.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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About This Trial
Individuals with stroke commonly experience both depression and cognitive difficulties. The goal of this study is to evaluate the efficacy of a treatment that combines a digital therapeutic (an iPad-based cognitive training program) with learning cognitive strategies. The hypotheses are that this treatment will improve cognitive skills, depression symptoms, daily function, and brain connectivity. …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * first-time stroke that occurred 6 months or more prior to study initiation * executive dysfunction as defined by a score of less than 1 standard deviation below age-adjusted normative score on at least one test of executive function in the screening assessment * diagnosis of M…
Contacts

Alexandra Keenan, BS

212-746-1509

alk4028@med.cornell.edu

CONTACT

Abhishek Jaywant, PhD

646-289-5204

abj2006@med.cornell.edu

CONTACT