No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
21 – 80
Sex
Any
Study type
Observational
Participants needed
8,000 (estimated)
Sponsor
National Heart Centre Singapore · Other
Who this trial is looking for
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The overall aim is to build an AI driven national Platform for CT cOronary angiography for clinicaL and industriaL applicatiOns (APOLLO) for automated anonymization, reporting, Agatston scoring and plaque quantification in CAD. It is a "one-stop" platform spanning diagnosis to clinical management and prognosis, and aid in predicting pharmacotherapy response.
Trial Locations
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Status
Eligibility Criteria
Inclusion Criteria:
1. Age ≥21 years old
2. Signed informed consent
3. Clinically indicated for evaluation by CTCA
Exclusion Criteria:
1. Individuals unable to provide informed consent
2. Known complex congenital heart disease
3. Planned invasive angiography for reasons other than CAD
4. Non-card…
Inclusion Criteria:
1. Age ≥21 years old
2. Signed informed consent
3. Clinically indicated for evaluation by CTCA
Exclusion Criteria:
1. Individuals unable to provide informed consent
2. Known complex congenital heart disease
3. Planned invasive angiography for reasons other than CAD
4. Non-cardiac illness with life expectancy \< 2 years
5. Pregnancy
6. Concomitant participation in another clinical trial in which subject is subject to investigational drug or device
7. Cardiac event and/or coronary revascularization (percutaneous coronary intervention (PCI) and/or coronary artery bypass grafting (CABG) and/or valvular repair/replacement prior to CTCA
8. Glomerular Filtration Rate ≤ 30mL/min
9. Known allergy to iodinated contrast agent
10. Contraindications to beta blockers or nitroglycerin or adenosine
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