Evaluating Buspirone to Treat Opioid Withdrawal

Recruiting Phase 2 Interventional Study
Opioid Use Disorder Opioid Withdrawal Opioid Craving Anxiety
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About This Trial
The investigators propose a rigorous, Phase II, three-group, placebo-controlled double-blind randomized controlled trial (RCT) to evaluate the efficacy of buspirone for both withdrawal and craving among individuals with opioid use disorder (OUD) undergoing a standardized stepwise taper. During this 10 to 12-day residential study, participants with OUD will be enrolled, stabilized on a short-acting…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Aged 18-75 * Opioid positive urine sample * Current moderate-severe opioid use disorder with evidence of physical dependence * Interested in undergoing opioid detoxification Exclusion Criteria: * Being pregnant or breastfeeding * Enrolled in methadone or buprenorphine mainte…
Contacts

Cecilia Bergeria, Ph.D.

410-550-1979

cberge21@jhmi.edu

CONTACT

Caitlyn Grubb, B.S.

410-550-0490

cgrubb7@jhmi.edu

CONTACT