Effect of Remimazolam and Propofol on Postoperative Delirium
Recruiting
N/A
Interventional Study
Hip Fractures
Knee Osteoarthritis
Femur Fracture
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 65 – 100
- Sex
- Any
- Study type
- Interventional
- Purpose
- Other
- Participants needed
- 82 (estimated)
- Sponsor
- Inje University · Other
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About This Trial
Remimazolam is an ultra-short acting benzodiazepine agonist which is used widely for general anesthesia and sedation. Remimazolam has several advantages. Remimazolam is rapidly metabolized by tissue esterase that it does not accumulate even after infusion for long periods of time. The presence of reversal agents (flumazenil) is also advantageous. Also, hemodynamic stability compared to propofol gi…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* elderly patients undergoing hip or knee arthroplasty under general anesthesia.
* body mass index \>30 kg/m2
Exclusion Criteria:
* moderate to severe liver dysfunction
* moderate to severe renal dysfunction
* unable to extubate in the operation room after operation
* benzodia…
Contacts