Exercise Program for High Blood Pressure in Binge Drinkers
Reducing Blood Pressure in Mid-life Adult Binge Drinkers
Recruiting
N/AInterventional Study
Alcohol DrinkingBinge DrinkingBlood PressureAlcohol AbstinenceAgingLifestyle FactorsVasodilationBehavioral Problem
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
50 – 64
Sex
Any
Study type
Interventional
Purpose
Prevention
Participants needed
55 (estimated)
Sponsor
The University of Texas at Arlington · Other
Who this trial is looking for
This trial is looking for men and women aged 50 to 64 who either do not drink alcohol, drink moderately, or binge drink. Participants will be involved in assessing their blood pressure and may go through an 8-week exercise program to see if it helps improve their condition.
Are You a Good Fit for This Trial?
You may be able to join if
I am between 50 and 64 years old.
I do not drink alcohol, drink moderately, or binge drink.
I can speak and understand English.
I am a postmenopausal woman.
You may not be able to join if
I have a history of diabetes.
I have a history of cardiovascular disease.
I have had an infection in the past 2 months.
I have high blood pressure (160/100 mm Hg or higher).
I have unstable body weight (more than 5% change in 6 months).
I use hormone replacement therapy.
I have a history of cancer.
I engage in regular aerobic exercise.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
This study has two phases:
Phase 1 is to examine blood pressure, microvascular function, and sympathetic nerve activity in mid-life adult binge drinkers vs. alcohol abstainers/moderate drinkers.
Phase 2 is to examine the effect of 8-week aerobic exercise training on blood pressure, microvascular function, and sympathetic nerve activity in mid-life adult binge drinkers
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Men and women (50-64 years of age) who do not drink alcohol, who drink at moderate levels, or who binge drink
* Female subjects will be postmenopausal (i.e., cessation of menses for ≥1 yr).
* Subjects who can speak and understand English.
Exclusion Criteria:
* a history of d…
Inclusion Criteria:
* Men and women (50-64 years of age) who do not drink alcohol, who drink at moderate levels, or who binge drink
* Female subjects will be postmenopausal (i.e., cessation of menses for ≥1 yr).
* Subjects who can speak and understand English.
Exclusion Criteria:
* a history of diabetes, cardiovascular disease, liver, or renal disease
* current or history of smoking and illicit drug use
* blood pressure ≥160/100 mm Hg
* other known traditional cardiovascular disease risks: obesity (BMI≥35 kg/m2), or hyperlipidemia (total cholesterol\>230 mg/dl and/or LDL cholesterol\>160 mg/dl)
* active infection (in the past 2 months)
* a history of seizures, cancer, or inflammatory disease (i.e., gout or rheumatoid)
* unstable body weight (\>5% change during the past 6 months)
* regular aerobic exercise training (i.e., they engage in 30 min of structured aerobic exercise at least 3 times per week)
* current use of hormone replacement therapy (i.e., estrogen, progesterone, and testosterone)
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