Topical 5-Fluorouracil Effervescent Powder in the Treatment of Vitiligo

Recruiting Phase 4 Interventional Study
Vitiligo Topical Fluorouracil Effervescent Mixture
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
10 – 70
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Treatment
Participants needed
60 (estimated)
Sponsor
Al-Azhar University · Other
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About This Trial
A novel approach for 5-Fluorouracil delivery based on a solid effervescent formulation is proposed . 5-Fluorouracil is water soluble (\~50mg/ml) and therefore has been used for the development of novel topical formulations including nano and microparticles intended for skin targeting. After hydration 5-Fluorouracil could form a complex, a suspension or even be formulated to generate effervescence.…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Patients who will be diagnosed as localized stable vitiligo. * Age older than 10 years * Stability of lesions for a duration of at least 1 year. * Patients who didn't receive treatment for vitiligo in the previous 6 weeks before starting the study. * Patients who agreed to joi…
Contacts

Neveen A. Kohaf, Ph.D

+201069482380

nevenabdo@azhar.edu.eg

CONTACT