Preoperative vs Postoperative Hypofractionated Radiosurgery for Patients With Large Brain Metastases

Recruiting N/A Interventional Study
Brain Metastases, Adult
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
146 (estimated)
Sponsor
Istituto Clinico Humanitas · Other
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About This Trial

This is a phase III randomized trial with the aim to compare preoperative HSRS to postoperative HSRS in patients with large at least one BMs from solid tumors suitable for surgical resection.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age \>18 years * Histological or cytological or radiological confirmation of solid tumor malignancy * Clinical indication for surgical resection of one brain metastasis * Karnosky performance status (KPS) ≥70 * Controlled or responsive extra cranial metastatic lesions * Limite…
Contacts

Pierina Navarria, MD

+39 028224 7458

pierina.navarria@cancercenter.humanitas.it

CONTACT

Federico Pessina, MD

+39 028224 4617

federico.pessina@hunimed.eu

CONTACT