VZV in the Enteric Nervous System: Pathogenesis and Consequences
Recruiting
Phase 4
Interventional Study
Achalasia
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 – 75
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 40 (estimated)
- Sponsor
- Vanderbilt University Medical Center · Other
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About This Trial
Varicella zoster virus (VZV) is the cause of chickenpox and shingles, but it also infects, becomes latent, and reactivates in nerve cells of the bowel to cause a gastrointestinal disorder ("enteric shingles"). The Investigators recently found that a chronic active VZV infection, a form of enteric shingles, is associated with achalasia, a severe disease in which the passage of food from esophagus t…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Male and female subjects aged 18-75 years old inclusive (females of childbearing potential should be on highly effective contraceptive methods)
* Fluent in English and mentally capable to provide informed consent who present to Vanderbilt University Medical Center Digestive Di…
Contacts