Deep Brain Stimulation for Parkinson's Disease Symptoms

Effects of Pallidal Deep Brain Stimulation Location on Motor Impairment in Parkinson's Disease

Recruiting N/A Interventional Study
Parkinson's Disease
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
21 – 89
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
24 (estimated)
Sponsor
University of Minnesota · Other
Who this trial is looking for

This trial is looking for people with Parkinson's disease who have had surgery to implant deep brain stimulators. Participants will help researchers understand how different locations of stimulation affect motor symptoms.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have been diagnosed with Parkinson's disease.
  • I have undergone surgery to implant deep brain stimulators.
  • I have existing 7T brain imaging.

You may not be able to join if

  • I have a history of movement issues due to musculoskeletal disorders.
  • I have another significant neurological disorder.
  • I have a history of dementia or cognitive impairment.
  • I have had post-operative complications or adverse effects.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial
This protocol will characterize the effects of deep brain stimulation (DBS) location (both adverse and beneficial) on motor signs in people with Parkinson's disease (PD). This information can be used to inform future DBS protocols to tailor stimulation to the specific needs of a patient. If targeted dorsal GP stimulation is shown to significantly improve motor features that are typically resistant…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * diagnosis of idiopathic PD * have undergone neurosurgery to implant deep brain stimulators in the globus pallidus (GP DBS) or subthalamic nucleus (STN) * Existing 7T brain imagery Exclusion Criteria: * history of musculoskeletal disorders that significantly affect movement o…
Contacts

Colum MacKinnon, PhD

cmackinn@umn.edu

CONTACT