An Open Labeled RCT on the Effect of Additional hCG Injection for LPS on Pregnancy Outcomes in IHH Patients
Recruiting
N/A
Interventional Study
Luteal Phase Deficiency
Luteal Phase Support
Idiopathic Hypogonadotropic Hypogonadism
At a Glance
- Age
- 18 – 45
- Sex
- Female
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 46 (estimated)
- Sponsor
- Fudan University · Other
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About This Trial
Luteal phase deficiency (LPD) accounts for most failures of assistant artificial reproduction (ART) and early pregnancy loss for patients with idiopathic hypogonadotropic hypogonadism (IHH). Luteal phase support (LPS) is one of the indispensable interventions in ART treatments for IHH patients, which includes progestin, estrogen, human chorionic gonadotropin (hCG), and GnRH agonists (GnRHa). We ai…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Clinical diagnosis of IHH (primary amenorrhea (with or without a history of hormone supplementation therapy); basic LH levels \<5IU/L, FSH\<5IU/L or normal; no organic lesions in the hypothalamus and pituitary MRI).
* Women of childbearing age who desire to get pregnant
Exclu…
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