LONGitudinal Multi-omics Phenotyping of KIDney Function Alteration
Recruiting
Observational Study
Chronic Kidney Diseases
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 – 75
- Sex
- Any
- Study type
- Observational
- Participants needed
- 20 (estimated)
- Sponsor
- Charite University, Berlin, Germany · Other
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About This Trial
This is a longitudinal observation of kidney function, immune system and gut microbiota before and 24 weeks after a live kidney transplantation conducted in donor and recipient pairs living in the same household. Outcome measures include kidney function, body composition, blood pressure, gut microbiome composition, metabolomics and immune cell states.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Body-Mass-Index 18,5 - 34,9 kg/m2
* Planned living kidney donation / transplantation
Exclusion Criteria:
* Clinically relevant heart, lung, liver, and kidney diseases
* Postoperative phase
* Acute infections
* Vegan diet
* Change of body weight of more than 10% in the month …
Contacts