Expanding Medication-Assisted Therapies in Central Asia
Recruiting
N/AInterventional Study
Opioid Use Disorder
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Health Services Research
Participants needed
900 (estimated)
Sponsor
Yale University · Other
Who this trial is looking for
This trial is looking for people with opioid dependence to help improve treatment options in Central Asia. Participants will share their experiences or be involved in assessments related to opioid agonist therapy.
Are You a Good Fit for This Trial?
You may be able to join if
I am 18 years or older
I meet the criteria for opioid dependence
I have never received opioid agonist therapy or I have been on it for less than 90 days
I currently work as an opioid agonist therapy delivery professional
You may not be able to join if
I am not willing to provide consent
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Central Asia (CA) represents the most rapidly growing HIV epidemic region worldwide, concentrated in people who inject drugs (PWID) and their sexual partners, and scaling up opioid agonist therapies (OAT) in this region is the most cost-effective strategy to prevent new HIV infections, and more effective when combined with antiretroviral therapy (ART). The investigators propose to use the Network …
Central Asia (CA) represents the most rapidly growing HIV epidemic region worldwide, concentrated in people who inject drugs (PWID) and their sexual partners, and scaling up opioid agonist therapies (OAT) in this region is the most cost-effective strategy to prevent new HIV infections, and more effective when combined with antiretroviral therapy (ART). The investigators propose to use the Network for the Improvement of Addiction Treatment (NIATx) implementation strategy to scale-up OAT in three diverse Central Asian countries (Kazakhstan, Kyrgyzstan, Tajikistan) and guided by the Exploration-Planning-Implementation-Sustainment (EPIS) framework. Understanding the trajectories of implementation and scale-up in this context may emerge through creating communities of practice, especially when cohesion and competence evolves, and may guide other healthcare delivery challenges in the region (e.g., HIV, TB); as well as build important regional expertise and understanding implementation trajectories should help support OAT program sustainability.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
i. Aim 1: The inclusion criteria for Aim 1 Consists of:
1. Quantitative surveys for PWID
1. 18 years or older
2. Meeting DSM-V criteria for opioid dependence
3. Be either treatment naïve and seeking OAT or be on OAT for \< 90 days
2. Organizational Assessments for OAT…
Inclusion Criteria:
i. Aim 1: The inclusion criteria for Aim 1 Consists of:
1. Quantitative surveys for PWID
1. 18 years or older
2. Meeting DSM-V criteria for opioid dependence
3. Be either treatment naïve and seeking OAT or be on OAT for \< 90 days
2. Organizational Assessments for OAT Delivery Staff
1. 18 years or older
2. Currently working as an OAT delivery professional at an OAT delivery site
3. Focus Groups (PWID on OAT)
1. 18 years or older
2. Meeting DSM-V criteria for opioid dependence
3. Be either treatment naïve and seeking OAT or be on OAT for \< 90 days
4. Focus Groups (PWID not on OAT)
1. 18 years or older
2. Meeting Diagnostic and Statistical Manual of Mental Disorders(DSM)-V criteria for opioid dependence
3. Be OAT naïve (defined as never having been on OAT or having not received treatment for \> 1 year)
5. Focus Groups (OAT delivery staff)
1. 18 years or older
2. Currently working as an OAT delivery professional at an OAT delivery site
ii. Aim 2: The inclusion criteria for Aim 2 consists of:
1. 18 years or older
2. Currently assigned as a Chief Narcologist for an Oblast
iii. Aim 3: The inclusion criteria for Aim 3 consists of:
1. 18 years or older
2. Authorized as a professional to work at an OAT delivery site
Exclusion Criteria:
* Not willing to provide consent
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