Thyroid Function and Structure in Klinefelter Syndrome
Recruiting
Observational Study
Klinefelter Syndrome
Thyroiditis, Autoimmune
Hypothyroidism
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 1 – 80
- Sex
- Male
- Study type
- Observational
- Participants needed
- 600 (estimated)
- Sponsor
- University of Roma La Sapienza · Other
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About This Trial
This is a longitudinal retrospective study for the evaluation of thyroid function and structure in patients with Klinefelter syndrome compared to healthy controls and patients affected by chronic lymphocytic thyroiditis.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Patients with a confirmed diagnosis of classic, non-mosaic 47,XXY Klinefelter syndrome based on a peripheral blood 97 karyotype analysis;
* Availability of thyroid function test results (TSH, fT3, and fT4) and/or thyroid US imaging;
* Availability of concurrent clinical data.
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Contacts