A2 to O Lung Transplants
Recruiting
N/A
Interventional Study
Lung Transplant
ABO Incompatibility
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 10 (estimated)
- Sponsor
- University Health Network, Toronto · Other
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About This Trial
Blood group A2 to blood group O kidney and liver transplants have been shown to be safe and successful, especially in recipients with low pre-operative anti-A antibody titers and with the use of peri-operative antibody-depleting therapies. Since blood group O lung transplant candidates tend to have longer wait times and a higher waitlist mortality compared to other blood groups, we propose to cond…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* first lung transplant
* blood group O recipient
* low pre-operative anti-A antibody titers
* consent to study participation
Exclusion Criteria:
* re-transplant
* multiorgan transplant
* positive virtual crossmatch at time of transplant
Contacts