No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
34 – 80
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
60 (estimated)
Sponsor
VA Office of Research and Development · Federal
Who this trial is looking for
This trial is looking for people who have experienced fatigue after a stroke over six months ago. Participants will receive a type of magnetic stimulation treatment to see if it helps improve their fatigue and mood.
Are You a Good Fit for This Trial?
You may be able to join if
I am more than 6 months post-stroke
I have clinically present fatigue
You may not be able to join if
I have conditions that make MRI or magnetic stimulation unsafe
I cannot follow simple three-step instructions
I have other diagnosed neurological conditions
I am pregnant
I have had strokes in the stimulation areas
I have severe hypertension
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
This experimental trial is investigating the use of magnetic stimulation of the brain as a possible treatment for post-stroke fatigue in people who have had a stroke more than six months prior to enrolling. Fatigue is a common condition after a stroke and can negatively impact an individual's ability to perform desired social and physical activities. Magnetic stimulation of the brain has been show…
This experimental trial is investigating the use of magnetic stimulation of the brain as a possible treatment for post-stroke fatigue in people who have had a stroke more than six months prior to enrolling. Fatigue is a common condition after a stroke and can negatively impact an individual's ability to perform desired social and physical activities. Magnetic stimulation of the brain has been shown to improve signs and symptoms of related psychological (e.g., depression) conditions. Participants in this trial will receive a type of magnetic stimulation called repetitive transcranial magnetic stimulation, or rTMS. The investigators will measure feelings of fatigue and other clinical characteristics related to mood and cognition before and after participants receive rTMS.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* More than 6 months post-stroke
* Clinically present fatigue
Exclusion Criteria:
* Contraindications to magnetic resonance imaging (MRI)/transcranial magnetic stimulation (TMS)/repetitive transcranial magnetic stimulation (rTMS), e.g., implanted metal within the head, history…
Inclusion Criteria:
* More than 6 months post-stroke
* Clinically present fatigue
Exclusion Criteria:
* Contraindications to magnetic resonance imaging (MRI)/transcranial magnetic stimulation (TMS)/repetitive transcranial magnetic stimulation (rTMS), e.g., implanted metal within the head, history of seizures
* Inability to follow simple three-step instructions
* Diagnosed comorbid neurological conditions (e.g. multiple sclerosis, Parkinson's disease, moderate/severe traumatic brain injury (TBI)
* Pregnancy
* Strokes within stimulation sites
* Pregnancy
* Severe hypertension (resting systolic blood pressure (SBP) \> 200, DBP \> 120)
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