Role of Autophagy in Type 2 Diabetes Microvascular Dysfunction
Recruiting
Early Phase 1
Interventional Study
Type 2 Diabetes
Healthy Aging
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 80
- Sex
- Any
- Trial phase
- Early Phase 1
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 60 (estimated)
- Sponsor
- Medical College of Wisconsin · Other
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About This Trial
The goal of this clinical trial is to examine the role of autophagy on microvascular function in adults with Type 2 Diabetes. The main question it aims to answer are:
* Does presence of Type 2 Diabetes reduce autophagy and impair microvascular function?
* Does exposure to high glucose impair autophagy and subsequently microvascular function?
Participants will undergo 2 study days. The primary ou…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: Participants must be between 18-80 yrs. of age and will be delineated into two groups
* Clinical Diagnosis of Type 2 Diabetes Mellitus in accordance with American Diabetes Association (ADA) guidelines (Type 2 Diabetic group)
* Otherwise healthy individuals (Healthy control group…
Contacts