Eccentric Exercise for Neuromuscular Diseases
Repeated Bout Effect i Neuromuscular Diseases
Recruiting
N/A
Interventional Study
Myopathy
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 50 (estimated)
- Sponsor
- Mads Peter Godtfeldt Stemmerik · Other
Who this trial is looking for
This trial is looking for adults with neuromuscular diseases to see how different types of exercise affect muscle damage. Participants will complete an exercise challenge to help researchers understand these effects.
Are You a Good Fit for This Trial?
You may be able to join if
- I am over 18 years old.
- I can complete the exercise challenge.
- I have a confirmed diagnosis of myopathy or am a healthy control.
- I have no active muscle injury on the test day.
You may not be able to join if
- I have a serious heart or lung condition.
- My veins are too difficult to puncture for blood tests.
- I have severe muscle weakness that stops me from completing the exercise test.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
The repeated bout effect (RBE) refers to the adaptation whereby a single bout of eccentric exercise protects against muscle damage from subsequent eccentric bouts. This effect has been shown in many muscle groups using both serum biomarkers, muscle soreness and imaging techniques. Though the effect is well described in healthy, it has never been studied in patients with neuromuscular diseases (NMD…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age \> 18 years
* The ability to complete the exercise challenge
* No concurrent medical condition that could interfere with interpretation of the results
* Molecular diagnosis of the specific condition in specified patient groups or healthy control
* No active muscle injury o…
Contacts