Phenotyping Heterogeneity and Regionality of the Aorta

Recruiting Observational Study
Large Artery Stiffness Aortic Disease Aortic Stenosis Aortic Aneurysm
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
300 (estimated)
Sponsor
Heinrich-Heine University, Duesseldorf · Other
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About This Trial
The aorta distributes cardiac stroke volume into the whole body through its finetuned conductance function, that is propagation and modulation of flow pattern. Physicomechanic properties of the aortic wall assure continuous and homogenous blood flow distribution to organs. The physicomechanic properties of the aortic wall are heterotopic: The collagen/elastin ratio doubles in the abdominal aorta a…
Trial Locations
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Eligibility Criteria
1. apparently healthy volunteers Inclusion Criteria: • Healthy volunteers Exclusion Criteria: * \< 18 years * Active Medication * Cardiovascular Disease * MRI not possible 2. Patients with Aortic Stenosis Inclusion Criteria: • Patients suffering from 3rd drgree Aortic…
Contacts

Christine Quast, MD

+492118118800

Christine.Quast@med.uni-duesseldorf.de

CONTACT

Lisa Dannenberg, MD

+49211 81 05315

LisaKristina.Dannenberg@med.uni-duesseldorf.de

CONTACT