Colonoscopy vs Stool Testing for Older Adults with Polyps

Colonoscopy vs Stool Testing for Older Adults With Colon Polyps

Recruiting N/A Interventional Study
Colorectal Polyp Colorectal Neoplasms Colorectal Adenoma Colorectal Cancer Digestive System Disease
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
65 – 82
Sex
Any
Study type
Interventional
Purpose
Prevention
Participants needed
8,946 (estimated)
Sponsor
Dartmouth-Hitchcock Medical Center · Other
Who this trial is looking for

This trial is looking for older adults aged 65-82 who have had colon polyps. Participants will compare two ways to monitor their health after having polyps: a colonoscopy or a stool test.

Are You a Good Fit for This Trial?
Rules you out Colorectal cancerGenetic syndrome for high colorectal cancer riskInflammatory bowel diseaseSevere heart diseaseSevere lung diseaseRecent strokeDementia affecting daily activitiesSevere liver disease

You may be able to join if

  • I speak English or Spanish
  • I have a personal history of colorectal polyps
  • My last colonoscopy showed 2 or fewer non-advanced polyps
  • I am due for a colonoscopy within the next 12 months
  • I can provide written informed consent

You may not be able to join if

  • I have a personal history of colorectal cancer
  • I have a genetic syndrome that increases my risk for colorectal cancer
  • I have inflammatory bowel disease
  • My last colonoscopy showed advanced polyps or 3 or more non-advanced polyps
  • I am unlikely to benefit from polyp surveillance due to certain health issues
  • I cannot provide written informed consent

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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About This Trial

This is a multi-site comparative effectiveness randomized controlled trial (RCT) comparing annual fecal immunochemical testing (FIT) and colonoscopy for post-polypectomy surveillance among adults aged 65-82 with a history of colorectal polyps who are due for surveillance colonoscopy.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * English or Spanish speaking * Personal history of colorectal polyps * Most recent colonoscopy with ≤2 non-advanced polyps * Currently due or coming due within 12 months for colonoscopy * Able to provide written informed consent Exclusion Criteria: * Personal history of color…
Contacts

Barbie Patel, MPH

857-4987233

coopstudy@hitchcock.org

CONTACT