Cognitive Behavioral Intervention for Pregnant Women
Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa
Recruiting
N/A
Interventional Study
Depression
Posttraumatic Stress Disorder
Pregnancy Related
Medication Adherence
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 15 and older
- Sex
- Female
- Study type
- Interventional
- Purpose
- Prevention
- Participants needed
- 118 (estimated)
- Sponsor
- Boston University Charles River Campus · Other
Who this trial is looking for
This trial is looking for pregnant women in South Africa who are HIV-negative and have challenges with taking a medication called PrEP. Participants will work on improving their mental health and PrEP adherence through a brief intervention.
Are You a Good Fit for This Trial?
You may be able to join if
- I am female
- I am aged 15 or older
- I am currently pregnant and attending antenatal care
- I am HIV-negative
- I started PrEP less than one month ago or have trouble taking it
- I have moderate to severe symptoms of posttraumatic stress and/or depression
You may not be able to join if
- I am unable to give informed consent or assent in English or Xhosa
- I have a significant psychiatric illness that could interfere with my participation
- I have health conditions that make it difficult for me to travel to the clinic
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
Pregnant women in South Africa (SA) are at high risk of HIV acquisition. Pre-exposure prophylaxis (PrEP) use during pregnancy is both safe and effective in preventing HIV. However, posttraumatic stress (associated with intimate partner violence and/or other traumas) and depression negatively impact PrEP adherence among women in SA. Addressing posttraumatic stress and depression will likely improve…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* For participants across all three aims are:
* Female sex
* Aged 15+
* Pregnant and presenting antenatal care at the Gugulethu MOU
* HIV-negative
* Recent PrEP initiation (\<1 month ago) or PrEP adherence challenges, either documented (\>2 weeks late to pick up PrEP …
Contacts