Anti-Inflammatory Medications for Elevated PSA Levels
Anti-inflammatory Drugs and Serum Prostate-Specific Antigen Test
Recruiting
Phase 4
Interventional Study
Prostate Cancer
Prostate Inflammation
PSA
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 – 80
- Sex
- Male
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 198 (estimated)
- Sponsor
- Albany Medical College · Other
Who this trial is looking for
This trial is looking for men with high PSA levels who may need further testing. Participants will take over-the-counter anti-inflammatory medications to see if their PSA levels decrease.
Are You a Good Fit for This Trial?
You may be able to join if
- I am a male between 18 and 80 years old.
- I have a PSA level greater than 3 ng/ml.
- I have had a normal digital rectal examination in the last two years.
- I do not have symptoms of a urinary tract infection.
You may not be able to join if
- I am allergic to ibuprofen or other NSAIDs.
- I have a history of stomach ulcers or bleeding.
- I have a bleeding disorder.
- I have severe chronic kidney disease.
- I have heart failure or significant heart disease.
- My high blood pressure is not well controlled.
- I have an active urinary tract infection.
- I have prostate cancer or had a prostate biopsy in the last year.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
Prostate cancer is the most frequently diagnosed cancer in men in the Unites States. Nearly 1 million prostate biopsy procedures are performed in the United States annually and elevated prostate-specific antigen (PSA) level is the primary reason for prostate biopsy in \> 90% of cases. However, at the PSA levels which trigger prostate biopsy, often no cancer is found in prostate biopsy specimens. P…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Male patients age between 18-80 years old with a screening PSA \> 3 ng/ml being considered for additional diagnostic testing (e.g., MRI, biopsy)
* Normal digital rectal examination within the past two years. A documented normal digital rectal examination by another physician o…
Contacts