Plant-Based Diet for MGUS or Smoldering Myeloma

A Study Comparing a Plant-Based Diet With Supplements and Placebo in People With Monoclonal Gammopathy of Undetermined Significance (MGUS) or Smoldering Multiple Myeloma (SMM)

Recruiting N/A Interventional Study
Monoclonal Gammopathy of Undetermined Significance Smoldering Multiple Myeloma
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
180 (estimated)
Sponsor
Memorial Sloan Kettering Cancer Center · Other
Who this trial is looking for

This trial is looking for people diagnosed with monoclonal gammopathy of undetermined significance (MGUS) or smoldering multiple myeloma (SMM). Participants will follow a plant-based diet for at least 12 weeks to see how it affects certain levels in their stool.

Are You a Good Fit for This Trial?
Must not be taking CurcuminOmega-3
Rules you out Heavy drinkingIllicit drug use

You may be able to join if

  • I have been diagnosed with MGUS or SMM.
  • I am at least 18 years old.
  • I am willing to follow the study procedures.
  • I can maintain a performance status between 0-3.
  • I want to learn how to cook plant-based recipes.

You may not be able to join if

  • I already follow a whole foods plant-based diet.
  • I have an allergy to legumes.
  • I have severe nut allergies.
  • I am currently in other diet or exercise programs.
  • I have a mental impairment affecting my cooperation.
  • I am pregnant.
  • I drink more than 2 alcoholic drinks per day.
  • I currently use illegal drugs.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer a few quick questions to see if you may meet the eligibility requirements.

Check Your Eligibility
About This Trial
The researchers are doing this study to look at how butyrate levels change in participants' stool after they are on a- plant-based diet for at least 12 weeks. All participants will have monoclonal gammopathy of undetermined significance (MGUS) or smoldering multiple myeloma (SMM). We will compare how the plant-based diet, omega-3 fatty acid and curcumin supplements, and placebo (an inactive substa…
Trial Locations
Loading…

Loading trial locations…

Eligibility Criteria
Inclusion Criteria: * Confirmed diagnosis of MGUS or SMM * If non light chain MGUS/SMM then M spike must be either ≥ 0.2 g/dL or BM PC ≥10% (both not required) * If light chain MGUS/SMM then involved must be ≥10 mg/dL or BM PC ≥10% (both not required) * If IgA MGUS/SMM then an IgA level \>350 mg/dL…
Contacts

Urvi A Shah, MD, MS

646-608-3713

ShahNutrivention@mskcc.org

CONTACT

Alexander Lesokhin, MD

646-608-3717

CONTACT