Feasibility of Reducing Respiratory Drive Using the Through-flow System
Recruiting
N/A
Interventional Study
Respiratory Insufficiency
Diaphragm Injury
Lung Injury
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Prevention
- Participants needed
- 15 (estimated)
- Sponsor
- University Health Network, Toronto · Other
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
Mechanical ventilation can lead to diaphragm and lung injury. During mechanical ventilation, the diaphragm could be completely rested or it could be overworked, either of which may cause diaphragm injury. Mechanical stress and strain applied by mechanical ventilation or by the patient's own respiratory muscles can also cause injury to the lungs. Diaphragm and lung injury are associated with increa…
Trial Locations
Loading…
Loading trial locations…
Eligibility Criteria
Inclusion Criteria:
* PaO2/FiO2 less than or equal to 300 at time of screening
* Oral endotracheal intubation with ETT 7.5 or 8.0 and on invasive mechanical ventilation
* Bilateral airspace opacities on chest radiograph or chest CT scan
Exclusion Criteria:
* Contraindication to esophageal cathete…
Contacts