Biomarker and Imaging Package Study in Immune Effector Cell-Associated Neurotoxicity Syndrome
Recruiting
Observational Study
Immune Effector Cell Associated Neurotoxicity Syndrome
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 – 80
- Sex
- Any
- Study type
- Observational
- Participants needed
- 50 (estimated)
- Sponsor
- zhang shoulong · Other
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About This Trial
CAR T-cell therapy is a promising innovative therapy for hematological malignancies. Immune effectors cells-associated neurotoxicity syndrome (ICANS) is a significant complication of CAR therapy. The goal of this study is to understand what brain mechanisms become disrupted when patients experience ICANS. The study will test the hypothesis that cerebrospinal fluid catecholamines and multimodal mag…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Subjects must be ≥ 18 years of age at signing of informed consent.
* Subjects are scheduled to receive CAR T-cell treatment.
Exclusion Criteria:
* Refusal to sign the informed consent
* Subjects having previously been treated with CAR-T therapy.
* Subjects with clinically si…
Contacts