Immune Profile Analysis and Biomarker Identification in Women With Repeated Implantation Failure or Unexplained Recurrent Spontaneous Miscarriage
Recruiting
N/A
Interventional Study
Repeated Embryo Implantation Failure
Recurrent Miscarriage
Immune System
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 39
- Sex
- Female
- Study type
- Interventional
- Purpose
- Other
- Participants needed
- 150 (estimated)
- Sponsor
- Centre Hospitalier Universitaire, Amiens · Other
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About This Trial
Implantation is a determining step in human reproduction which requires the transition from a pro-inflammatory state to an anti-inflammatory state allowing the implantation of a competent embryo within a receptive endometrium, and then the maternal immunotolerance towards the alloantigenic fetus. Repeat implantation failures (RIFs), that refers to the fail to achieve a clinical pregnancy after the…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* For patients :
* Women aged 18 to 39 years
* women with a history of RIF or unexplained RM
* women with a negative diagnostic work-up (including pelvic ultrasound and hysteroscopy, parental karyotype, thyroid function test, and anti-thyroid and anti-phospholipid antibodies)
* …
Contacts