Acute Stroke: Prehospital Versus In-HospitAL Initiation of Recanalization Therapy- ASPHALT

Inclusion Criteria: * Emergency call to one of the two following emergency medical service (EMS) dispatch centers : SAMU (Service d'Aide Médicale Urgente) or BSPP (Brigade des Sapeurs Pompiers de Paris), between 08:00 and 18:00, 5 days a week (Monday to Friday). * Suspected acute stroke according to a dispatcher stroke identification algorithm, adapted from the ROSIER scale * Symptom onset-to-randomization time ≤ 6h * Patient located within the predefined catchment area of the MSU * MSU available at the time of the EMS call * Informed consent (as approved by the ethics committee, informed consent will be obtained after randomization: at the arrival of the MSU (intervention group), or at hospital arrival (control group)) Exclusion Criteria: * Patient confined to be more than 50% of waking hours * Unknown or uncertain onset time (e.g. wake-up stroke) * Medical history of epilepsy * Recent epileptic seizure (\<12 hrs) * Suspicion of pregnancy * Parturient or breastfeeding woman * Patient already participating in another interventional study, which could influence the mRS at 3 months. * Patient under guardianship or curatorship * Patient not affiliated to French Social Security