The Six Food Elimination in Postprandial Distress Syndrome

Inclusion Criteria: * Functional dyspepsia patients with meal related symptoms (Rome IV Postprandial Distress Syndrome, PDS) * Witnessed written informed consent prior to any study procedures * Patients aged between 18 and 70 years inclusive * Male or female patients * Women of child-bearing potential agree to apply a highly effective method of birth control during the entire duration of the trial. Women of non-childbearing potential may be included if surgically sterile or postmenopausal with at least 2 year without spontaneous menses. * Subject is capable to understand the study and the questionnaires, and to comply with the study requirements. Exclusion Criteria: * History of gastrointestinal surgery (other than appendectomy). * Organic gastro-intestinal disease * Major psychiatric disorder * Patients with eosinophilic esophagitis * Presence of diabetes mellitus * Presence of coeliac disease, lupus, scleroderma and other systemic auto-immune disease. * Active H. Pylori infection or \< 6 months after eradication * Predominant irritable bowel syndrome (IBS) * Predominant gastro-oesophageal reflux disease (GERD) * Atopic constitution or food allergy * Ongoing diet which interferes with the 6 food elimination diet. * Drugs altering gastric emptying or anti-inflammatory drugs * Females who are pregnant or lactating * Patients not capable to understand or be compliant with the study.