The Role of the Gastrointestinal-associated Lymphoid Tissue in the Cure of HIV Infection

Inclusion Criteria: * Provision of signed and dated informed consent form * Stated willingness to comply with all study procedures and lifestyle considerations and availability for the duration of the study * Males and females; Age 18-75 * Chronic HIV-1 infection, documented by any licensed rapid HIV test or HIV enzyme or chemiluminescence immunoassay (E/CIA) test kit at any time prior to study entry and confirmed by a licensed Western blot or a second antibody test by a method other than the initial rapid HIV and/or E/CIA, or by HIV-1 antigen, plasma HIV-1 RNA viral load * Receiving treatment with a molecule with the potential for HIV cure * Willingness and ability to undergo colonoscopy twice during the study timeframe Exclusion Criteria: * Known coagulopathy or altered coagulation studies * Concomitant pregnancy of plans for pregnancy during the study period * Concomitant Inflammatory Bowel Disease, Diarrheal disease or other gastrointestinal disease that might alter the intestinal mucosal tissue * Concomitant sexually transmitted infection * Any other condition which in the opinion of investigators would impede competence, compliance or possibly hinder completion of the study