No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 – 100
Sex
Any
Study type
Interventional
Purpose
Prevention
Participants needed
150 (estimated)
Sponsor
University of Pittsburgh · Other
Who this trial is looking for
This trial is looking for adults who are scheduled for knee or hip surgery and have moderate mood disorder symptoms. Participants will use the RxWell platform to help manage their mood around the time of surgery.
Are You a Good Fit for This Trial?
You may be able to join if
I am over 18 years old.
I am having elective knee or hip surgery.
I have moderate mood disorder symptoms.
You may not be able to join if
I am having emergency surgery.
I have a serious cognitive condition.
I do not have access to a smartphone or tablet.
I have active alcohol or drug abuse issues.
I have severe mood disorders needing immediate help.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
It is envisioned that multipronged benefits from this pilot work for the UPMC ISD and its members. It is expected the RxWell platform to provide the following benefits: expansion of the use of RxWell to all UPMC ISD members providing peri-operative mood management with advantage of improved peri-operative outcomes, improving saving for the UPMC ISD by hastening the recovery and decreased resource …
It is envisioned that multipronged benefits from this pilot work for the UPMC ISD and its members. It is expected the RxWell platform to provide the following benefits: expansion of the use of RxWell to all UPMC ISD members providing peri-operative mood management with advantage of improved peri-operative outcomes, improving saving for the UPMC ISD by hastening the recovery and decreased resource utilization, and addition to the high-value care of UPMC with this holistic approach to patient perioperative care
Trial Locations
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Eligibility Criteria
Inclusion Criteria for the RXWell Study:
* Adults \>18 years
* Scheduled for elective primary total knee arthroplasty (TKA) or hip replacement (THA) at the approved UPMC hospitals
* Moderately high levels of mood disorder symptoms on validated PROMIS measures, defined as a T-score \> or = to 60 on …
Inclusion Criteria for the RXWell Study:
* Adults \>18 years
* Scheduled for elective primary total knee arthroplasty (TKA) or hip replacement (THA) at the approved UPMC hospitals
* Moderately high levels of mood disorder symptoms on validated PROMIS measures, defined as a T-score \> or = to 60 on PROMIS Anxiety 4a short form and/or PROMIS Depression4a short form
Exclusion Criteria for the RXWell Study:
* Patients undergoing non-elective surgery or secondary arthroplasty
* Active delirium, neurocognitive impairment, or severe intellectual disability
* No access to a smart device (phone or tablet)
* Active alcoholism (defined as daily use of more than 1 liter of wine and /or 3 or more shots of hard liquor) or drug abuse (defined as daily use of illicit drugs)
* Profound mood disorders requiring immediate intervention such as suicidal ideation, defined as a PROMIS Depression score of more than 70
* A PROMIS Anxiety and/or Depression T-score \>70, which corresponds to severe anxiety and depression.
* Patients needing immediate care will be referred to psychiatrists and primary team.
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