Rocket Study: A Study to Characterize Biomarkers and Disease Progression in Participants With Pelizaeus-Merzbacher Disease

Recruiting Observational Study
Pelizaeus-Merzbacher Disease
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
6 Months – 17
Sex
Male
Study type
Observational
Participants needed
32 (estimated)
Sponsor
Ionis Pharmaceuticals, Inc. · Industry
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About This Trial
The purpose of the study is to prospectively assess longitudinal changes in proteolipid protein 1 (PLP1) protein, disease-related biomarkers in cerebral spinal fluid (CSF) and blood, neuroimaging parameters relevant to Pelizaeus-Merzbacher disease (PMD) and longitudinal changes in performance on clinical, participant, and caregiver-reported outcome assessments to inform the development of therapie…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Participant has a parent or caregiver capable of providing informed consent (signed and dated) and able to attend all scheduled study visits and provide feedback regarding the participant's symptoms and performance as described in the protocol and be able to comply with all s…
Contacts

Ionis Pharmaceuticals

(844) 430-1848

IonisPelizaeusMerzbacherStudy@clinicaltrialmedia.com

CONTACT