Impairments of Neuro-muscular Communication in Motor-Neuron Disease: A Bio-Marker for Early and Personalised Diagnosis
Recruiting
Observational Study
ALS (Amyotrophic Lateral Sclerosis)
Postpoliomyelitis Syndrome
Spinal Muscular Atrophy
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 400 (estimated)
- Sponsor
- University of Dublin, Trinity College · Other
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About This Trial
Motor neuron disease (MND) or ALS is a nervous system disease. ALS leads to a loss of movement ability that eventually leads to death. At the moment, there is no known treatment for ALS. Early diagnosis in individuals improves clinical care and facilitates timely entry into clinical trials. However, current methods for diagnosis are primarily clinical, and to date, no cost-effective biomarkers hav…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
Healthy Volunteers:
* age and gender-matched to patient groups
* the intact physical ability to take part in the experiment.
Patients:
* Diagnosis of ALS, PLS, PMA, SMA, Polio or MS
* capable of providing informed consent.
Exclusion Criteria:
Healthy Controls:
* History of…
Contacts