Veno-arterial ExtraCorporeal Membrane Oxygenation to Reduce Morbidity and Mortality Following Lung TransPlant

Recruiting N/A Interventional Study
The Number of Ventilator-free Days in the 28 Days Following LT
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Supportive Care
Participants needed
200 (estimated)
Sponsor
Assistance Publique - Hôpitaux de Paris · Other
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About This Trial
In patients undergoing lung transplantation (LT), the investigators hypothesize that a "systematic" intraoperative ECMO strategy would reduce the need for invasive mechanical ventilation in the first 28 days without increasing adverse events, as compared to an "on-demand" intraoperative ECMO strategy. To date, LT remains a highly hazardous procedure. Even if the surgical procedure is well establi…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: Age \>18 years Assessed for bilateral sequential lung transplantation for obstructive or restrictive lung disease Affiliation to the French social security Written informed consent Exclusion Criteria: At listing : * a pulmonary hypertension with a mPAP \> 45 mmHg, including i…
Contacts

Jonathan MESSIKA, MD

+33 1 46 25 59 84

j.messika@hopital-foch.com

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