Transcranial Stimulation for Focal and Generalized Epilepsy

Study of Transcranial Direct Current Stimulation to Treat Epilepsy

Recruiting N/A Interventional Study
Focal Epilepsy Generalized Onset Epilepsy Sleep-related Epileptic Encephalopathy
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
6 and older
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
30 (estimated)
Sponsor
Mayo Clinic · Other
Who this trial is looking for

This trial is looking for people with certain types of epilepsy who have ongoing seizures. Participants will receive electrical stimulation on the scalp to see if it helps reduce seizures.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have been diagnosed with generalized onset or focal epilepsy or sleep-related epileptic encephalopathy.
  • I have at least 2 countable seizures per month.
  • I have not found control with at least 2 anti-seizure medicines.
  • I can keep my medication constant during the study.
  • I can understand consent and keep a seizure diary in English.

You may not be able to join if

  • I have a disease that is likely to progress during the study.
  • I have psychogenic non-epileptic seizures.
  • I have attempted suicide or been hospitalized for psychiatric reasons in the past 2 years.
  • I have a skin condition that interferes with scalp electrodes or I am allergic to silver.
  • I am pregnant or not able to verify that I am not pregnant.
  • I have implanted devices like a pacemaker, except for VNS.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

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About This Trial

The purpose of this research is to see to what extent electrical stimulation applied to the scalp (transcranial direct current stimulation or tDCS) can reduce the number and intensity of epileptic seizures.

Trial Locations
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Eligibility Criteria
Inclusion Criteria * Clinical diagnosis of generalized onset or focal epilepsy or sleep-related epileptic encephalopathy. * Estimated to have at least 2 countable seizures per month or spike-wave index ≥50%. * Has not had control with at least 2 anti-seizure medicines. * Able to maintain a constant…
Contacts

Precylla Ruiz

507-538-6606

ruiz.precylla@mayo.edu

CONTACT

Izzie Meunier

507-538-6337

meunier.isabelle@mayo.edu

CONTACT