Paclitaxel Injection for Urethral Stricture Treatment
Role of Paclitaxel in Stricture Urethra
- Age
- 18 and older
- Sex
- Male
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 200 (estimated)
- Sponsor
- Al-Azhar University · Other
This trial is looking for men with a specific type of urethra narrowing called anterior urethral stricture. Participants will receive an injection of paclitaxel after a common procedure to help improve the treatment results.
You may be able to join if
- I have been diagnosed with anterior urethral stricture
- My stricture is less than 2 cm long
- I have a low International Prostate Symptom Score
- My maximum urine flow rate is less than 15 ml per second
- I have not received any previous treatment for my stricture
You may not be able to join if
- I have had repeated problems with urethral strictures
- I have had pelvic radiation treatment before
- I have other related health issues like bladder neck contracture
- I have a neurogenic bladder
- I have benign prostatic hyperplasia
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your EligibilityStricture urethra is a common disease and has various causing factors. The most common performed procedure is direct visual internal urethrotomy (DVIU), but unfortunately has a high recurrence rates. Multiple trial were performed to improve the outcomes of DVIU. Various intralesional injections were used. in this trial we will evaluate intralesional paclitaxel injection following DVIU.
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