Tissue Destruction and Healing in Celiac Disease
Recruiting
N/A
Interventional Study
Celiac Disease
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 75
- Sex
- Any
- Study type
- Interventional
- Purpose
- Diagnostic
- Participants needed
- 220 (estimated)
- Sponsor
- University of Chicago · Other
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About This Trial
The purpose of this clinical study is to learn more about celiac disease pathogenesis and clinical symptoms. In particular, this study will examine the interactions between biological factors such as, intestinal epithelial cells, microbiota, immune system, genetics, and gluten and their effect on celiac disease clinical symptoms, and severity of tissue destruction and its ability to heal in indivi…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
Gluten challenge group:
1. Age 18 to 75 years old
2. Diagnosis of Celiac disease for at least 12 months by intestinal biopsy
3. Follow a strict gluten-free diet for at least the 12 consecutive months
Gluten de-challenge group:
1. Age 18 to 75 years old
2. Showing typical celi…
Contacts