Defining the Natural History of Squamous Cell Carcinoma in Fanconi Anemia
Recruiting
Observational Study
Fanconi Anemia
Inherited Bone Marrow Failure Syndrome
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 8 – 90
- Sex
- Any
- Study type
- Observational
- Participants needed
- 200 (estimated)
- Sponsor
- National Cancer Institute (NCI) · NIH
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About This Trial
Background:
Fanconi anemia (FA) is an inherited disorder. People with FA are more likely to get certain cancers, especially squamous cell carcinoma (SCC). These cancers usually appear first in the mouth, esophagus, and genital and anal areas. Early detection of SCCs may help improve survival rates for people with FA.
Objective:
This natural history study will regularly screen people with FA for…
Trial Locations
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Eligibility Criteria
* INCLUSION CRITERIA:
1. On referral, persons \>= 12 years with FA primarily from North America will be included. An individual with FA who is 8 - 11 years can also be included if they have a history of persistent OPMLs, dysphagia, or other concerning symptoms.
2. Individuals with prior cancer …
Contacts