HP Pyruvate MRI in Cancers
Recruiting
Phase 1
Phase 2
Interventional Study
Image
Warburg Effect
Tumors
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 – 88
- Sex
- Any
- Trial phase
- Phase 1/2
- Study type
- Interventional
- Purpose
- Diagnostic
- Participants needed
- 25 (estimated)
- Sponsor
- University of Maryland, Baltimore · Other
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About This Trial
Many human diseases are characterized by their ability to alter existing metabolic pathways and interrupt cellular processes. Cancer exploits the Warburg effect and utilizes greater glucose than normal cells and within this process uses anaerobic respiration, leading to increased conversion of pyruvate to lactate. This can be exploited by hyperpolarized imaging. Hyperpolarized 13C MRI imaging is a…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
Clinical tumor diagnosis
Patients with pre-existing MR imaging appointments
Must be able to undergo MR
Exclusion Criteria:
No tumor diagnosis
Contacts
No contact information available.