Motivational Behavioral and Functional MRI Impairment in Patients With Chronic Neuropathic Pain
Recruiting
Observational Study
Chronic Pain
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 50 (estimated)
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild · Research network
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About This Trial
The main hypothesis of this study is that the alteration of the reward circuitry underlying the motivational deficit in chronic pain patients compared to healthy subjects results in a decrease in the capacity for reward learning. The fMRI studies have shown that this type of learning depends on the dopaminergic system innervating key regions of the reward system.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* For cases: patients managed in the neurosurgery department or at CETD for chronic neuropathic pain, of central or peripheral origin.
* For controls: matched to a case on age (±5 years) and sex
Exclusion Criteria:
* Neurodegenerative or inflammatory neurological pathology
* C…
Contacts
No contact information available.