Intra-articular Injection for Rhizarthrosis Pain
Tolerance of Intra-articular Injection Autologous Stromal Vascular Fraction for the Treatment of Rhizarthrosis
Recruiting
Phase 2
Interventional Study
Rhizarthrosis
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Phase 2
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 12 (estimated)
- Sponsor
- University Hospital, Rouen · Other
Who this trial is looking for
This trial is looking for people with rhizarthrosis who have not found relief from pain after at least 6 months of treatment. Participants will receive an injection of a specialized cell treatment directly into the joint of the thumb.
Are You a Good Fit for This Trial?
You may be able to join if
- I have been diagnosed with rhizarthrosis stage 1 to 3
- I have been on treatment for my symptoms for 6 months or more
- I experience pain that rates at least 4 out of 10
- I have a Quick Dash or PRWHE score of 20 or more out of 100
- I am affiliated with a social security scheme
- I have read and understood the information about the trial
- I have signed the consent form
You may not be able to join if
- I have had an injection into my thumb joint in the last 6 months
- My Body Mass Index is less than 18 kg/m2
- I have a contraindication to local anesthesia or general anesthesia
- I have a blood disorder that would prevent liposuction
- I have a severe allergy to common antibiotics
- I have a known allergy to human albumin or any related products
- I have an infection near where the injection will happen
- I am scheduled for hand or upper limb surgery during the trial
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
Rhizarthosis is a common disease in the population (15%). It has a major impact on the function of the hand since it compromises the pollicidigitales claws and all gripping functions with the thumb. However, no curative medical treatment exists to date. The treatment is initially based on a symptomatic approach: analgesics, non-steroidal anti-inflammatories, immobilization orthoses or even intra-a…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Rhizarthrosis DELL stage 1 to 3
* Symptomatic medical treatment for a period of at least 6 months (analgesic, orthosis, anti-inflammatory, etc. or intra-articular infiltration of the trapezio-metacarpal joint) which has become ineffective (surgical stage)
* EVA pain ≥ 4
* Quic…
Contacts