External Pharyngeal Exerciser and Pharyngeal Phase of Swallowing
Recruiting
N/AInterventional Study
Dysphagia
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 85
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
60 (estimated)
Sponsor
Medical College of Wisconsin · Other
Who this trial is looking for
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
This study of healthy young and elderly individuals is intended to assess the effects of pharyngeal exerciser on pharyngeal pressure phenomenon during swallowing. Our specific aim is to test if the pharyngeal exerciser increases the workload of muscles involved in pharyngeal phase of swallowing.
Trial Locations
Sorted by distance from Kentucky
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Status
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Eligibility Criteria
Inclusion Criteria:
* Healthy volunteers must be at least 18 years of age or older.
Exclusion Criteria:
* Subjects with cervical spine disorders.
* Subjects with neurological disorders like dementia, cerebrovascular diseases other than Parkinson's Disease
* Subjects with carotid artery bruit or c…
Inclusion Criteria:
* Healthy volunteers must be at least 18 years of age or older.
Exclusion Criteria:
* Subjects with cervical spine disorders.
* Subjects with neurological disorders like dementia, cerebrovascular diseases other than Parkinson's Disease
* Subjects with carotid artery bruit or carotid vascular disorders.
* Subjects suffering from muscle diseases like muscular dystrophies, myopathies.
* Subjects with neuro-muscular junction disorders myasthenia gravis, Eaton-Lambert disorders.
* Subjects with any current esophageal symptoms like heartburn, dysphagia, chest pain or regurgitation.
* Subjects cannot have previous head or neck surgery or radiation.
* Subjects unable to tolerate nasal intubation.
* Subjects with significant bleeding disorders for whom nasal intubation has been deemed contraindicated.
* Subjects with a known upper airway or esophageal obstruction preventing the passage of the manometry probe.
* Subjects with autonomic dysfunction.
* Subjects having a history of allergy to lidocaine and barium.
* Subjects who are pregnant or lactating.
* Subjects who have advanced medical disorders (e.g.: chronic obstructive pulmonary disease (COPD), congestive heart failure, cirrhosis, cancer, chronic renal failure, etc.).
* Subjects who are medically unstable.
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