Neurostimulation for Mood and Emotion Regulation Issues

Neurostimulation Versus Therapy for Problems With Emotions

Recruiting N/A Interventional Study
Emotion Regulation Mood Disorders Stress Disorder Anxiety Disorders OCD Impulse Control Disorder Eating Disorders Emotional Dysfunction Emotional Instability Emotional Distress Emotional Maladjustment Emotional Impulsivity Obsessive-Compulsive Disorder Emotion Dysregulation Borderline Personality Disorder
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 55
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
240 (estimated)
Sponsor
Duke University · Other
Who this trial is looking for

This trial is looking for adults who struggle with managing emotions and have mood or anxiety disorders. Participants will receive training on emotion regulation skills and a type of brain stimulation in a single session.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am between 18 and 55 years old.
  • I have difficulties in regulating my emotions.
  • I have been in the same type of therapy for at least one month.
  • I have low use of cognitive restructuring.
  • I have a diagnosis of a mood, anxiety, OCD, impulse control, or eating disorder.
  • I agree to keep my medication the same throughout the study.
  • I have not had rTMS before.

You may not be able to join if

  • I am currently experiencing hypomania.
  • I have a current or past psychotic disorder.
  • I have been diagnosed with Bipolar I disorder.
  • I have a current substance use disorder.
  • I cannot read or consent to this study.
  • I weigh over 300 pounds.
  • I am pregnant.
  • I have had TMS before.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

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About This Trial
The primary goal of this clinical trial is to evaluate the unique neural and behavioral effects of a one-session training combining emotion regulation skills training, with excitatory repetitive transcranial magnetic stimulation (rTMS) over the dorsolateral prefrontal cortex (dlPFC). The secondary aim is to identify key changes in the emotion regulation neural network following the combined interv…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * age 18 to 55 * elevated overall score on Difficulties with Emotion Regulation Scale (DERS total score \>=90) * has been in the same type of psychotherapy (including none) for the last 4 weeks/1mo (\*except for current CBT) and is willing to stay on the same regimen throughout …
Contacts

Zoe Brasher

9196846785

zoe.brasher@duke.edu

CONTACT

Lisalynn D Kelley, CCRP

9196846701

lisalynn.kelley@duke.edu

CONTACT